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DATABASE-LICEDB: light industrial core enzyme database for industrial applications and AI enzyme design

发布日期:2025-01-14 00:00:00   浏览量 :26
发布日期:2025-01-14 00:00:00  
26

Lei Gong, Fufeng Liu, Chuanxi Zhang, Yongfan Ming, Yulan Mou, ZhaoTingYuan, Haiming Jiang , Bei Gao, Fuping Lu, Lujia Zhang

        Enzymes, serving as eco-friendly catalysts, are progressively supplanting traditional chemical catalysts in light industry sectors such as feed, papermaking, textiles, detergents, leather, and sugar production. Despite this advancement, the variability in the performance of natural enzymes and the fragmentation and diversity of existing data formats pose significant challenges to researchers. Furthermore, AI-driven enzyme design is limited by the quality and quantity of available data. To address these issues, we introduce the light industrial core enzyme database (LICEDB), the first database dedicated exclusively to managing and standardizing enzymes for light industry applications. LICEDB, with its integrated modules for data retrieval, similarity analysis, and structural analysis, will enhance the efficient industrial application of enzymes and strengthen AI-driven predictive research, thereby advancing data sharing and utilization in the field of enzyme innovation.

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